sentence( id(1) date(2008.4.1) validators(Automatic) sentence_form(Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65) -mediated induction of the c-rel gene.) structure( mood(involve~0, indicative) obj(involve~0, coord~18) stmt_type(involve~0, declarative) subj(involve~0, activation~2) tense(involve~0, pres) vtype(involve~0, main) adjunct(activation~2, human~4) adjunct(activation~2, of~6) mod(activation~2, T-cell~11) mod(activation~2, Tax~5) mod(activation~2, leukemia~12) mod(activation~2, type~14) mod(activation~2, virus~13) num(activation~2, sg) pers(activation~2, 3) adegree(human~4, positive) adjunct_type(human~4, nominal) atype(human~4, attributive) num(Tax~5, sg) pers(Tax~5, 3) adjunct_type(of~6, nominal) obj(of~6, B/Rel~7) ptype(of~6, semantic) mod(B/Rel~7, NF-kappa~9) num(B/Rel~7, sg) pers(B/Rel~7, 3) num(NF-kappa~9, sg) pers(NF-kappa~9, 3) num(T-cell~11, sg) pers(T-cell~11, 3) num(leukemia~12, sg) pers(leukemia~12, 3) num(virus~13, sg) pers(virus~13, 3) adjunct(type~14, I~16) num(type~14, sg) pers(type~14, 3) adjunct_type(I~16, label) conj(coord~18, coord~22) conj(coord~18, induction~31) coord_form(coord~18, and) coord_level(coord~18, NP) num(coord~18, pl) pers(coord~18, 3) adjunct_type(of~20, nominal) obj(of~20, I kappa B alpha~26) ptype(of~20, semantic) adjunct(coord~22, of~20) conj(coord~22, degradation~25) conj(coord~22, phosphorylation~24) coord_form(coord~22, and) coord_level(coord~22, N) num(coord~22, pl) pers(coord~22, 3) num(phosphorylation~24, sg) pers(phosphorylation~24, 3) num(degradation~25, sg) pers(degradation~25, 3) num(I kappa B alpha~26, sg) pers(I kappa B alpha~26, 3) adjunct(induction~31, mediate~1001) adjunct(induction~31, of~37) num(induction~31, sg) pers(induction~31, 3) adjunct(RelA~33, p65~35) num(RelA~33, sg) pers(RelA~33, 3) adjunct_type(p65~35, parenthetical) num(p65~35, sg) pers(p65~35, 3) adjunct_type(of~37, nominal) obj(of~37, gene~38) ptype(of~37, semantic) det_form(gene~38, the) det_type(gene~38, def) mod(gene~38, c-rel~42) num(gene~38, sg) pers(gene~38, 3) num(c-rel~42, sg) pers(c-rel~42, 3) adjunct_type(mediate~1001, nominal) atype(mediate~1001, attributive) mod(mediate~1001, RelA~33) passive(mediate~1001, +)) ) sentence( id(2) date(2008.4.1) validators(Automatic) sentence_form(The tax gene product of human T-cell leukemia virus type I (HTLV-I) is a potent transcriptional activator that both stimulates viral gene expression and activates an array of cellular genes involved in T-cell growth.) structure( mood(be~0, indicative) stmt_type(be~0, declarative) subj(be~0, product~2) tense(be~0, pres) vtype(be~0, copular) xcomp(be~0, activator~20) adjunct(product~2, of~9) det_form(product~2, the) det_type(product~2, def) mod(product~2, gene~7) mod(product~2, tax~6) num(product~2, sg) pers(product~2, 3) num(tax~6, sg) pers(tax~6, 3) num(gene~7, sg) pers(gene~7, 3) adjunct_type(of~9, nominal) obj(of~9, type~10) ptype(of~9, semantic) adjunct(type~10, HTLV-I~13) adjunct(type~10, I~19) adjunct(type~10, human~12) mod(type~10, T-cell~15) mod(type~10, leukemia~16) mod(type~10, virus~17) num(type~10, sg) pers(type~10, 3) adegree(human~12, positive) adjunct_type(human~12, nominal) atype(human~12, attributive) adjunct_type(HTLV-I~13, parenthetical) num(HTLV-I~13, sg) pers(HTLV-I~13, 3) num(T-cell~15, sg) pers(T-cell~15, 3) num(leukemia~16, sg) pers(leukemia~16, 3) num(virus~17, sg) pers(virus~17, 3) adjunct_type(I~19, label) adjunct(activator~20, coord~44) adjunct(activator~20, potent~42) adjunct(activator~20, transcriptional~43) det_form(activator~20, a) det_type(activator~20, indef) num(activator~20, sg) pers(activator~20, 3) subj(activator~20, product~2) adegree(potent~42, positive) adjunct_type(potent~42, nominal) atype(potent~42, attributive) adegree(transcriptional~43, positive) adjunct_type(transcriptional~43, nominal) atype(transcriptional~43, attributive) adjunct(coord~44, coord~48) adjunct_type(coord~44, relative) conj(coord~44, activate~56) conj(coord~44, stimulate~50) coord_form(coord~44, and) coord_level(coord~44, VPall) pron_rel(coord~44, pro~45) topic_rel(coord~44, pro~45) num(pro~45, sg) pers(pro~45, 3) pron_form(pro~45, that) pron_type(pro~45, relative) adjunct_type(coord~48, relative) coord_form(coord~48, both) mood(stimulate~50, indicative) obj(stimulate~50, expression~51) stmt_type(stimulate~50, declarative) subj(stimulate~50, pro~45) tense(stimulate~50, pres) vtype(stimulate~50, main) adjunct(expression~51, viral~53) mod(expression~51, gene~55) num(expression~51, sg) pers(expression~51, 3) adegree(viral~53, positive) adjunct_type(viral~53, nominal) atype(viral~53, attributive) num(gene~55, sg) pers(gene~55, 3) mood(activate~56, indicative) obj(activate~56, array~57) stmt_type(activate~56, declarative) subj(activate~56, pro~45) tense(activate~56, pres) vtype(activate~56, main) adjunct(array~57, of~61) det_form(array~57, a) det_type(array~57, indef) num(array~57, sg) pers(array~57, 3) adjunct_type(of~61, nominal) obj(of~61, gene~62) ptype(of~61, semantic) adjunct(gene~62, cellular~64) adjunct(gene~62, involve~65) num(gene~62, pl) pers(gene~62, 3) adegree(cellular~64, positive) adjunct_type(cellular~64, nominal) atype(cellular~64, attributive) adjunct_type(involve~65, nominal) obl(involve~65, in~67) passive(involve~65, +) subj(involve~65, pro~1001) vtype(involve~65, main) obj(in~67, growth~68) ptype(in~67, semantic) mod(growth~68, T-cell~70) num(growth~68, sg) pers(growth~68, 3) num(T-cell~70, sg) pers(T-cell~70, 3) pron_type(pro~1001, null)) ) sentence( id(3) date(2008.4.1) validators(Automatic) sentence_form(Tax acts indirectly by inducing or modifying the action of various host transcription factors, including members of the NF-kappa B/Rel family of enhancer-binding proteins.) structure( adegree(enhancer-binding~32, positive) adegree(indirectly~4, positive) adegree(various~17, positive) adjunct(action~10, of~14) adjunct(act~0, by~5) adjunct(act~0, indirectly~4) adjunct(factor~15, include~18) adjunct(factor~15, various~17) adjunct(family~22, of~29) adjunct(member~19, of~21) adjunct(protein~30, enhancer-binding~32) adjunct_type(enhancer-binding~32, nominal) adjunct_type(include~18, nominal) adjunct_type(of~14, nominal) adjunct_type(of~21, nominal) adjunct_type(of~29, nominal) adjunct_type(various~17, nominal) adv_type(by~5, vpadv) adv_type(indirectly~4, vpadv) atype(enhancer-binding~32, attributive) atype(various~17, attributive) conj(coord~6, induce~8) conj(coord~6, modify~9) coord_form(coord~6, or) coord_level(coord~6, V) det_form(action~10, the) det_form(family~22, the) det_type(action~10, def) det_type(family~22, def) mod(factor~15, host~34) mod(factor~15, transcription~35) mod(family~22, B/Rel~27) mod(family~22, NF-kappa~26) mood(act~0, indicative) num(B/Rel~27, sg) num(NF-kappa~26, sg) num(action~10, sg) num(factor~15, pl) num(family~22, sg) num(host~34, sg) num(member~19, pl) num(protein~30, pl) num(tax~2, sg) num(transcription~35, sg) obj(by~5, coord~6) obj(include~18, member~19) obj(induce~8, action~10) obj(modify~9, action~10) obj(of~14, factor~15) obj(of~21, family~22) obj(of~29, protein~30) pers(B/Rel~27, 3) pers(NF-kappa~26, 3) pers(action~10, 3) pers(factor~15, 3) pers(family~22, 3) pers(host~34, 3) pers(member~19, 3) pers(protein~30, 3) pers(tax~2, 3) pers(transcription~35, 3) prog(include~18, +) prog(induce~8, +) prog(modify~9, +) pron_type(pro~1001, null) pron_type(pro~1002, null) stmt_type(act~0, declarative) subj(act~0, tax~2) subj(induce~8, pro~1002) subj(modify~9, pro~1001) tense(act~0, pres) vtype(act~0, main) vtype(induce~8, main) vtype(modify~9, main) ) ) sentence( id(4) date(2008.4.1) validators(Automatic) sentence_form(In resting T cells\, many of these NF-kappa B/Rel factors are sequestered in the cytoplasm by various ankyrin-rich inhibitory proteins\, including I kappa B alpha.) structure( adegree(ankyrin-rich~26, positive) adegree(inhibitory~27, positive) adegree(various~25, positive) adjunct(cell~4, rest~6) obl(many~13, factor~16) partitive(many~13, +) num(many~13, pl) pers(many~13, 3) adjunct(protein~23, ankyrin-rich~26) adjunct(protein~23, include~28) adjunct(protein~23, inhibitory~27) adjunct(protein~23, various~25) adjunct(sequester~0, in~3) adjunct(sequester~0, in~9) adjunct_type(ankyrin-rich~26, nominal) adjunct_type(include~28, nominal) subj(include~28, pro~1001) pron_type(pro~1001, null) adjunct_type(inhibitory~27, nominal) adv_type(in~3, sadv) adv_type(in~9, sadv) adjunct_type(rest~6, nominal) adjunct_type(various~25, nominal) atype(ankyrin-rich~26, attributive) atype(inhibitory~27, attributive) atype(various~25, attributive) det_form(cytoplasm~10, the) det_form(factor~16, this) det_type(cytoplasm~10, def) det_type(factor~16, demon) mod(cell~4, T~8) mod(factor~16, B/Rel~21) mod(factor~16, NF-kappa~20) mood(sequester~0, indicative) num(I kappa B alpha~29, sg) num(B/Rel~21, sg) num(cell~4, pl) num(cytoplasm~10, sg) num(factor~16, pl) num(NF-kappa~20, sg) num(protein~23, pl) num(T~8, sg) obj(include~28, I kappa B alpha~29) obj(in~3, cell~4) obj(in~9, cytoplasm~10) obl_ag(sequester~0, protein~23) ptype(protein~23, nonsemantic) pcase(protein~23, by) passive(sequester~0, +) pers(I kappa B alpha~29, 3) pers(B/Rel~21, 3) pers(cell~4, 3) pers(cytoplasm~10, 3) pers(factor~16, 3) pers(NF-kappa~20, 3) pers(protein~23, 3) pers(T~8, 3) prog(include~28, +) prog(rest~6, +) ptype(in~3, semantic) ptype(in~9, semantic) stmt_type(sequester~0, declarative) subj(sequester~0, many~13) tense(sequester~0, pres) vtype(sequester~0, main) ) ) sentence( id(5) date(2008.4.1) validators(Automatic) sentence_form(HTLV-I Tax expression leads to the constitutive nuclear expression of biologically active NF-kappa B and c-Rel complexes; however, the biochemical mechanism (s) underlying this response remains poorly understood.) structure( conj(coord~0, lead~3) conj(coord~0, remain~30) coord_form(coord~0, ;) coord_level(coord~0, ROOT) mood(lead~3, indicative) obl(lead~3, to~10) stmt_type(lead~3, declarative) subj(lead~3, expression~4) tense(lead~3, pres) vtype(lead~3, main) mod(expression~4, HTLV-I~8) mod(expression~4, Tax~6) num(expression~4, sg) pers(expression~4, 3) num(Tax~6, sg) pers(Tax~6, 3) num(HTLV-I~8, sg) pers(HTLV-I~8, 3) obj(to~10, expression~11) ptype(to~10, semantic) adjunct(expression~11, constitutive~15) adjunct(expression~11, nuclear~16) adjunct(expression~11, of~17) det_form(expression~11, the) det_type(expression~11, def) num(expression~11, sg) pers(expression~11, 3) adegree(constitutive~15, positive) adjunct_type(constitutive~15, nominal) atype(constitutive~15, attributive) adegree(nuclear~16, positive) adjunct_type(nuclear~16, nominal) atype(nuclear~16, attributive) adjunct_type(of~17, nominal) obj(of~17, complex~27) ptype(of~17, semantic) conf(coord~18, NF-kappa B~26) conj(coord~18, c-Rel~29) coord_form(coord~18, and) coord_level(coord~18, NN) num(coord~18, pl) pers(coord~18, 3) adegree(active~22, positive) adjunct(active~22, biologically~24) adjunct_type(active~22, nominal) atype(active~22, attributive) adegree(biologically~24, positive) adv_type(biologically~24, amod) num(NF-kappa B~26, sg) pers(NF-kappa B~26, 3) adjunct(complex~27, active~22) mod(complex~27, coord~18) num(complex~27, pl) pers(complex~27, 3) num(c-Rel~29, sg) pers(c-Rel~29, 3) adjunct(remain~30, however~32) mood(remain~30, indicative) stmt_type(remain~30, declarative) subj(remain~30, mechanism~39) tense(remain~30, pres) vtype(remain~30, main) xcomp(remain~30, understand~44) adegree(however~32, positive) adv_type(however~32, sadv) adegree(biochemical~37, positive) adjunct_type(biochemical~37, nominal) atype(biochemical~37, attributive) adjunct(mechanism~39, biochemical~37) adjunct(mechanism~39, underlie~40) det_form(mechanism~39, the) det_type(mechanism~39, def) num(mechanism~39, pl) pers(mechanism~39, 3) adjunct_type(underlie~40, nominal) obj(underlie~40, response~41) prog(underlie~40, +) subj(underlie~40, pro~1001) vtype(underlie~40, main) deixis(response~41, proximal) det_form(response~41, this) det_type(response~41, demon) num(response~41, sg) pers(response~41, 3) adjunct(understand~44, poorly~57) passive(understand~44, +) subj(understand~44, mechanism~39) adegree(poorly~57, positive) adv_type(poorly~57, vpadv) pron_type(pro~1001, null) vtype(pro~1001, main)) ) sentence( id(6) date(2008.4.1) validators(Automatic) sentence_form(In this study\, we demonstrate that Tax-stimulated nuclear expression of NF-kappa B in both HTLV-I-infected and Tax-transfected human T cells is associated with the phosphorylation and rapid proteolytic degradation of I kappa B alpha.) structure( adegree(HTLV-I-infected~23, positive) adegree(Tax-stimulated~11, positive) adegree(Tax-transfected~25, positive) adegree(human~26, positive) adegree(nuclear~12, positive) adegree(proteolytic~38, positive) adegree(rapid~40, positive) adjunct(cell~18, coord~21) adjunct(cell~18, human~26) adjunct(coord~31, of~29) adjunct(degradation~36, proteolytic~38) adjunct(degradation~36, rapid~40) adjunct(demonstrate~0, in~3) adjunct(expression~9, Tax-stimulated~11) adjunct(expression~9, in~17) adjunct(expression~9, nuclear~12) adjunct(expression~9, of~13) adjunct_type(Tax-stimulated~11, nominal) adjunct_type(coord~21, nominal) adjunct_type(human~26, nominal) adjunct_type(in~17, nominal) adjunct_type(nuclear~12, nominal) adjunct_type(of~13, nominal) adjunct_type(of~29, nominal) adjunct_type(proteolytic~38, nominal) adjunct_type(rapid~40, nominal) adv_type(in~3, sadv) atype(HTLV-I-infected~23, attributive) atype(Tax-stimulated~11, attributive) atype(Tax-transfected~25, attributive) atype(human~26, attributive) atype(nuclear~12, attributive) atype(proteolytic~38, attributive) atype(rapid~40, attributive) comp(demonstrate~0, associate~8) conj(coord~21, HTLV-I-infected~23) conj(coord~21, Tax-transfected~25) conj(coord~31, degradation~36) conj(coord~31, phosphorylation~35) coord_form(coord~21, and) coord_form(coord~31, and) coord_level(coord~21, AP) coord_level(coord~31, N) deixis(study~4, proximal) det_form(coord~31, the) det_form(study~4, this) det_type(coord~31, def) det_type(study~4, demon) mod(cell~18, T~24) mood(associate~8, indicative) mood(demonstrate~0, indicative) num(I kappa B alpha~41, sg) num(NF-kappa B~16, sg) num(T~24, sg) num(cell~18, pl) num(coord~21, pl) num(coord~31, pl) num(degradation~36, sg) num(expression~9, sg) num(phosphorylation~35, sg) num(pro~7, pl) num(study~4, sg) obj(in~17, cell~18) obj(in~3, study~4) obj(of~13, NF-kappa B~16) obj(of~29, I kappa B alpha~41) obj(with~28, coord~31) obl(associate~8, with~28) passive(associate~8, +) pers(I kappa B alpha~41, 3) pers(NF-kappa B~16, 3) pers(T~24, 3) pers(cell~18, 3) pers(coord~21, 3) pers(coord~31, 3) pers(degradation~36, 3) pers(expression~9, 3) pers(phosphorylation~35, 3) pers(pro~7, 1) pers(study~4, 3) pron_form(pro~7, we) pron_type(pro~7, pers) ptype(in~17, semantic) ptype(in~3, semantic) ptype(of~13, semantic) ptype(of~29, semantic) ptype(with~28, semantic) quant(cell~18, both~1001) stmt_type(associate~8, declarative) stmt_type(demonstrate~0, declarative) subj(associate~8, expression~9) subj(demonstrate~0, pro~7) subord_form(associate~8, that) tense(associate~8, pres) tense(demonstrate~0, pres) vtype(associate~8, main) vtype(demonstrate~0, main) ) ) sentence( id(7) date(2008.4.1) validators(Automatic) sentence_form(In contrast to prior in vitro studies, at least a fraction of the phosphorylated form of I kappa B alpha remains physically associated with the NF-kappa B complex in vivo but is subject to rapid degradation, thereby promoting the nuclear translocation of the active NF-kappa B complex.) structure( adegree(active~134, positive) adegree(in vitro~9, positive) adegree(nuclear~128, positive) adegree(phosphorylate~21, positive) adegree(physically~50, positive) adegree(prior~11, positive) adegree(rapid~119, positive) adegree(subject~98, positive) adegree(thereby~123, positive) adjunct(associate~51, in vivo~77) adjunct(associate~51, physically~50) adjunct(be~80, promote~121) adjunct(complex~130, active~134) adjunct(contrast~4, to~6) adjunct(coord~0, in~3) adjunct(degradation~117, rapid~119) adjunct(form~17, of~22) adjunct(form~17, phosphorylate~21) adjunct(fraction~13, at least~15) adjunct(promote~121, thereby~123) adjunct(study~7, in vitro~9) adjunct(study~7, prior~11) adjunct(translocation~124, nuclear~128) adjunct(translocation~124, of~129) adjunct_type(active~134, nominal) adjunct_type(at least~15, nominal) adjunct_type(in vitro~9, nominal) adjunct_type(nuclear~128, nominal) adjunct_type(of~129, nominal) adjunct_type(of~22, nominal) adjunct_type(phosphorylate~21, nominal) adjunct_type(prior~11, nominal) adv_type(promote~121, sadv) subj(promote~121, pro~1001) pron_type(pro~1001, null) adjunct_type(rapid~119, nominal) adjunct_type(to~6, nominal) ptype(to~6, semantic) adv_type(in vivo~77, vpadv) adv_type(in~3, sadv) adv_type(physically~50, vpadv) adv_type(thereby~123, sadv) atype(active~134, attributive) atype(in vitro~9, attributive) atype(nuclear~128, attributive) atype(phosphorylate~21, attributive) atype(prior~11, attributive) atype(rapid~119, atributive) atype(subject~98, predicative) conj(coord~0, be~80) conj(coord~0, remain~31) coord_form(coord~0, but) coord_level(coord~0, VPall) det_form(complex~130, the) det_form(complex~71, the) det_form(form~17, the) det_form(fraction~13, a) det_form(translocation~124, the) det_type(complex~130, def) det_type(complex~71, def) det_type(form~17, def) det_type(fraction~13, indef) det_type(translocation~124, def) mod(complex~130, NF-kappa B~136) mod(complex~71, NF-kappa B~75) mood(be~80, indicative) mood(remain~31, indicative) num(I kappa B alpha~23, sg) num(NF-kappa B~136, sg) num(NF-kappa B~75, sg) num(at least~15, sg) num(complex~130, sg) num(complex~71, sg) num(contrast~4, sg) num(degradation~117, sg) num(form~17, sg) num(fraction~13, sg) num(study~7, pl) num(translocation~124, sg) obj(in~3, contrast~4) obj(of~129, complex~130) obj(of~22, I kappa B alpha~23) obj(promote~121, translocation~124) obj(to~116, degradation~117) ptype(to~116, semantic) obj(to~6, study~7) obj(with~70, complex~71) obl(associate~51, with~70) obl(fraction~13, form~17) obl(subject~98, to~116) partitive(fraction~13, +) passive(associate~51, +) passive(phosphorylate~21, +) pers(I kappa B alpha~23, 3) pers(NF-kappa B~136, 3) pers(NF-kappa B~75, 3) pers(at least~15, 3) pers(complex~130, 3) pers(complex~71, 3) pers(contrast~4, 3) pers(degradation~117, 3) pers(form~17, 3) pers(fraction~13, 3) pers(study~7, 3) pers(translocation~124, 3) prog(promote~121, +) ptype(in~3, semantic) ptype(of~129, semantic) ptype(of~22, semantic) ptype(with~70, semantic) stmt_type(coord~0, declarative) stmt_type(promote~121, declarative) subj(associate~51, fraction~13) subj(be~80, fraction~13) subj(coord~0, fraction~13) subj(remain~31, fraction~13) subj(subject~98, fraction~13) tense(be~80, pres) tense(remain~31, pres) vtype(be~80, copular) vtype(promote~121, main) vtype(remain~31, main) xcomp(be~80, subject~98) xcomp(remain~31, associate~51) ) ) sentence( id(8) date(2008.4.1) validators(Automatic) sentence_form(We further demonstrate that Tax induction of nuclear c-Rel expression is activated by the RelA (p65) subunit of NF-kappa B, which activates transcription of the c-rel gene through an intrinsic kappa B enhancer element.) structure( num(c-rel~36, 3) pers(c-rel~36, sg) adegree(far~4, comparative) adegree(intrinsic~43, positive) adegree(nuclear~12, positive) adjunct(RelA~17, p65~21) adjunct(activate~26, through~38) adjunct(demonstrate~0, far~4) adjunct(element~39, intrinsic~43) mod(expression~10, c-Rel~13) adjunct(expression~10, nuclear~12) mod(gene~32, c-rel~36) adjunct(induction~6, of~9) mod(induction~6, Tax~8) mod(subunit~15, RelA~17) adjunct(subunit~15, activate~26) adjunct(subunit~15, of~22) adjunct(transcription~29, of~31) adjunct_type(activate~26, nominal) adv_type(far~4, sadv) adjunct_type(intrinsic~43, nominal) adjunct_type(nuclear~12, nominal) adjunct_type(of~22, nominal) adjunct_type(of~31, nominal) adjunct_type(of~9, nominal) adjunct_type(p65~21, parenthetical) adv_type(through~38, vpadv) atype(intrinsic~43, attributive) atype(nuclear~12, attributive) comp(demonstrate~0, activate~5) det_form(RelA~17, the) det_form(element~39, a) det_form(gene~32, the) det_type(RelA~17, def) det_type(element~39, indef) det_type(gene~32, def) mod(element~39, enhancer~47) mod(element~39, kappa B~45) mood(activate~26, indicative) mood(activate~5, indicative) mood(demonstrate~0, indicative) num(NF-kappa B~25, sg) num(RelA~17, sg) num(c-Rel~13, sg) num(element~39, sg) num(enhancer~47, sg) num(expression~10, sg) num(gene~32, sg) num(induction~6, sg) num(kappa B~45, sg) num(p65~21, sg) num(pro~2, pl) num(pro~27, sg) num(subunit~15, sg) num(Tax~8, sg) num(transcription~29, sg) obj(activate~26, transcription~29) subj(activate~26, pro~27) obj(of~22, NF-kappa B~25) obj(of~31, gene~32) obj(of~9, expression~10) obj(through~38, element~39) obl_ag(activate~5, subunit~15) passive(activate~5, +) pcase(subunit~15, by) pers(NF-kappa B~25, 3) pers(RelA~17, 3) pers(c-Rel~13, 3) pers(element~39, 3) pers(enhancer~47, 3) pers(expression~10, 3) pers(gene~32, 3) pers(induction~6, 3) pers(kappa B~45, 3) pers(p65~21, 3) pers(pro~2, 1) pers(pro~27, 3) pers(subunit~15, 3) pers(Tax~8, 3) pers(transcription~29, 3) pron_form(pro~2, we) pron_form(pro~27, which) pron_rel(activate~26, pro~27) pron_type(pro~2, pers) pron_type(pro~27, relative) psem(subunit~15, nonsemantic) ptype(of~22, semantic) ptype(of~31, semantic) ptype(of~9, semantic) stmt_type(activate~26, declarative) stmt_type(activate~5, declarative) stmt_type(demonstrate~0, declarative) subj(activate~5, induction~6) subj(demonstrate~0, pro~2) subord_form(activate~5, that) tense(activate~26, pres) tense(activate~5, pres) tense(demonstrate~0, pres) topic_rel(activate~26, pro~27) vtype(activate~26, main) vtype(activate~5, main) vtype(demonstrate~0, main) ) ) sentence( id(9) date(2008.4.1) validators(Automatic) sentence_form(In normal cells, the subsequent accumulation of nuclear c-Rel acts to inhibit its own continued production, indicating the presence of an autoregulatory loop.) structure( adegree(autoregulatory~23, positive) adegree(continue~12, positive) adegree(normal~6, positive) adegree(nuclear~32, positive) adegree(own~11, positive) adegree(subsequent~28, positive) adjunct(accumulation~24, of~29) adjunct(accumulation~24, subsequent~28) adjunct(act~0, indicate~13) adjunct(act~0, inhibit~7) adjunct(act~0, in~3) adjunct(c-Rel~30, nuclear~32) adjunct(cell~4, normal~6) adjunct(loop~19, autoregulatory~23) adjunct(presence~14, of~18) adjunct(production~8, continue~12) adjunct(production~8, own~11) adjunct_type(autoregulatory~23, nominal) adjunct_type(continue~12, nominal) adjunct_type(normal~6, nominal) adjunct_type(nuclear~32, nominal) adjunct_type(of~18, nominal) adjunct_type(of~29, nominal) adjunct_type(own~11, nominal) adjunct_type(subsequent~28, nominal) adv_type(indicate~13, sadv) adv_type(inhibit~7, sadv) adv_type(in~3, sadv) atype(autoregulatory~23, attributive) atype(continue~12, attributive) atype(normal~6, attibutive) atype(nuclear~32, attributive) atype(own~11, attributive) atype(subsequent~28, attibutive) det_form(accumulation~24, the) det_form(loop~19, a) det_form(presence~14, the) det_type(accumulation~24, def) det_type(loop~19, indef) det_type(presence~14, def) inf_form(inhibit~7, to) mood(act~0, indicative) num(accumulation~24, sg) num(c-Rel~30, sg) num(cell~4, pl) num(loop~19, sg) num(presence~14, sg) num(production~8, sg) num(pro~9, sg) obj(indicate~13, presence~14) obj(inhibit~7, production~8) obj(in~3, cell~4) obj(of~18, loop~19) obj(of~29, c-Rel~30) passive(continue~12, +) pers(accumulation~24, 3) pers(c-Rel~30, 3) pers(cell~4, 3) pers(loop~19, 3) pers(presence~14, 3) pers(production~8, 3) pers(pro~9, 3) poss(production~8, pro~9) prog(indicate~13, +) pron_form(pro~9, it) pron_type(pro~9, pers) ptype(in~3, semantic) ptype(of~18, semantic) ptype(of~29, semantic) stmt_type(act~0, declarative) vtype(indicate~13, main) subj(indicate~13, pro~1002) pron_type(pro~1002, null) stmt_type(inhibit~7, purpose) subj(inhibit~7, pro~1001) pron_type(pro~1001, null) vtype(inhibit~7, main) subj(act~0, accumulation~24) tense(act~0, pres) vtype(act~0, main) ) )